IRB Procedures

Important Note

Please be sure to renew your CITI training every 3 years before submitting an IRB proposal.
CITI Research Ethics and Compliance Training

Cayuse for Human Ethics

If you have submitted proposals via Cayuse 424, no action is required; you will see the Cayuse IRB option listed when you log into using single sign on. If you have not submitted proposals via Cayuse 424 and you do not see the Cayuse IRB option, you will need to submit a request to gain access to the system via this link: Please note, the turnaround time to gain access can take up to 72 hours.

Firefox is the preferred browser.  Some components of the Cayuse site may not work properly on other browsers. 

Cayuse IRB is a system used for electronically preparing, submitting, and routing studies for IRB approval. All information is stored in the cloud and can be accessed securely from any location, making it simple for multiple simultaneous users to view and share documents. Users receive electronic notifications whenever an action is required on their part, allowing the study to proceed through each step of the process from study creation to final approval.

Any and all communication (i.e. actions taken, review memos, approval letters) related to your protocols will be handled in the system. You will receive notifications from Cayuse to your email.


We have a step-by-step submission guide available on our website to walk you through the process of submitting a protocol.

Contact Information

If you have questions or issues related to the content as you are submitting your protocol, please email us at or call 940-565-4643.

If you have software or technical issues while completing your protocol in the system, please contact

Research Integrity Compliance